J. A. Maddry, S. Ananthan, R. C. Goldman, J. V. Hobrath, C. D. Kwong, C. Maddox, L. Rasmussen, R. C. Reynolds, J. A. Secrist, M. I. Sosa, E. L. White, W. Zhang. Antituberculosis Activity of the Molecular Libraries Screening Center Network Library. Tuberculosis 89:354-363, 2009.
S. Ananthan, E. R. Faaleolea, R. C. Goldman, J. V. Hobrath, C. D. Kwong, B. E. Laughon, J. A. Maddry, A. Mehta, L. Rasmussen, R. C. Reynolds, J. A. Secrist III, N. Shindo, D. N. Showe, M. I. Sosa, W. J. Suling, E. L. White. High Throughput Screening for Inhibitors of Mycobacterium tuberculosis H37Rv. Tuberculosis 89:334-353, 2009.
W.E. Severson, M. McDowell, S. Ananthan, D.H. Chung, L. Rasmussen, M.I. Sosa, E.L. White, J. Noah, C.B. Jonsson. High-Throughput Screening of a 100,000 Compound Library for Inhibitors of Influenza A Virus (H3N2). J. Biomol. Screen. 13: 879-87,2008.
C.B. Maddox, L. Rasmussen, E.L. White. Adapting Cell Based Assays to the High Throughput Screening Platform: Problems Encountered and Lessons Learned. J. Assoc. Lab. Automation 13:168-73, 2008.
L. Rasmussen, C.B. Maddox, B. Harten, E. L. White. A Successful LIMS Implementation: Case Study at Southern Research Institute. J. Assoc. Lab. Automation. 12: 384-390, 2007.
E.L. White, K. Southworth, L. Ross, S. Cooley, R.B. Gill, M.I. Sosa, A. Manouvakhova, L. Rasmussen, C. Goulding, D. Eisenberg, and T.M. Fletcher III. A Novel Inhibitor of Mycobacterium tuberculosis Pantothenate Synthetase. J. Biomol. Screen. 12: 100-105, 2007.
W. E. Severson, N. Shindo, M.I. Sosa, T.M. Fletcher III, E.L. White, S. Ananthan, and C.B. Jonsson. Development and Validation of a High Throughput Screen for Inhibitors of SARS CoV and its Application in Screening a 100,000 Compound Library. J. Biomol. Screen. 12: 33-40, 2007.
J.W. Noah, W. Severson, D.L. Noah, L. Rasmussen, E.L. White, and C.B. Jonsson. A Cell-based Luminescence Assay is Effective for High-throughput Screening of Potential Influenza Antivirals. Antiviral Research 73: 50-9, 2007
R.C. Reynolds, L. Seitz, V. Pathak, W. Barrow, L.J. Ross, E.L. White, and W. Suling. 2,4-Diamino-5-deaza-6-Substituted Pteridines as Antitubercular Agents. J.Med.Chem. 2005.
D.W. Borhani and E.L.White. Polymerization of C-terminally Truncated Mycobacterium tuberculosis FtsZ is unlikely to be physiologically relevant. Microbiol. 150: 2903-3906, 2004.
A.K.W. Leung, E.L. White, L.J. Ross, R.C. Reynolds, J.A. DeVito, and D.W. Borhani. Structure of the Mycobacterium tuberculosis FtsZ Reveals Unexpected G Protein-like Conformational Switches. J. Mol. Biol. 342: 953-970, 2004.
R.C. Reynolds, S. Srivastava, L.J. Ross, W.J. Suling, and E.L. White. A New 2-Carbamoyl Pteridine that Inhibits Mycobacterial FtsZ. Bioorg. Med. Chem. Lett. 14: 3161-4, 2004.
E.L. White, L.J. Ross, A. Cunningham, and V .Escuyer. Cloning, Expression, and Characterization of Mycobacterium tuberculosis Dihydrofolate Reductase. FEMS Microbiol. Lett. 232: 101-5, 2004.
E.L. White, W.J. Suiling, L.J. Ross, L.E. Seitz, and R.D. Reynolds. 2-Alkoxycarbonylaminopyridines: Inhibitors of Mycobacterium tuberculosis FtsZ. J. Antimicrob. Chenother. 50: 111-4, 2002.
R.W. Buckheit, Jr., K. Watson, V. Fliaks-Boltz, J. Russell, T.L. Loftus, M.C. Osterling, J.A. Turpin, L.A. Pallansch, E.L. White, J.W. Lee, S.H. Lee, J.W. Oh, H.S. Kwon, S.G. Chung, and E.H. Cho. SJ-3366, a Unique and Highly Potent Nonnucleoside Reverse Transcriptase Inhibitor of Human Immunodeficiency Virus Type 1 (HIV-1) that also Inhibits HIV-2. Antimicrob. Agents Chemother. 45: 393-400, 2001.
E.L. White, L.J. Ross, R.C. Reynolds, L.E. Seitz, G.D. Moore and D.W. Borhani. The Slow Polymerization of Mycobacterium tuberculosis FtsZ. J. Bacteriol. 182: 4028-4034, 2000.
E.L. White, L.J. Ross, R.L. Davis, S.Z. van Ginkel, G. Vasanthakumar, and D.W. Borhani. The Two Toxoplasma gondii Hypoxanthine-Guanine Phosphoribosyltransferase Isozymes form Heterotetramers. J. Biol. Chem. 275: 19218-19223, 2000.
A. Héroux, E.L. White, L.J. Ross, R.L. Davis, A.P. Kuzin, and D.W. Borhani. Substrate Deformation in a Hypoxanthine-Guanine Phosphoribosyltransferase Ternary Complex: The Structural Basis for Catalysis. Structure 8: 1309-1318, 2000.
E.L. White, L.J. Ross, V.E.Steele, G.J. Kelloff, and D.L. Hill. Screening of Cancer Preventing Chemicals as Aromatase Inhibitors In Vitro. Anticancer Res. 19: 1017-1020 1999.
R.W. Buckheit, Jr., C. Lackman-Smith, M.J. Snow, S.M. Halliday, E.L. White, L.J. Ross, V.K. Agrawal, and A.D. Broom. PMTI, a Broadly Active Unusual Single-Stranded Polyribonucleotide, Inhibits HIV Replication by Multiple Mechanisms. Antiviral Chem. Chemother. 5: 23-32, 1999.
E.L. White, W. Chao, L.J. Ross, D.W. Borhani, P.D. Hobbs, U. Velapartha, and M.I. Dawson. Michellamine Alkaloids Inhibit Protein Kinase C. Arch. Biochem. Biophys. 365: 25-30, 1999.
E.L. White, L.J. Ross, P.D. Hobbs, U. Velapartha, and M.I. Dawson. Antioxidant Activity of Michellamine Alkaloids. Anticancer Res. 19: 1033-1035, 1999.
R.W. Buckheit, Jr., E.L. White, V. Fliakas-Boltz, J.Russell, T.L. Stup, T.L. Kinjerski, M.C. Osterling, A. Weigand, and J.P. Bader. Unique Anti-Human Immunodeficiency Virus activity of the Nonnucleoside Reverse Transcriptase Inhibitors Calanolide A, Costatolide A, and Dihydrococostatolide. Antimicrob. Agents Chemother. 43:1827-1834, 1999.
A. Héroux, E.L. White, L.J. Ross, R.L. Davis, and D.W. Borhani. Crystal Structure of Toxoplasma gondii Hypoxanthine-Guanine Phosphoribosyltransferase with XMP, Pyrophosphate, and Two Mg2+ Ions Bound: Insights into the Catalytic Mechanism. Biochemistry 38: 14495-14506, 1999.
A. Héroux, E.L. White, L.J. Ross, and D.W. Borhani. Crystal Structures of the Toxoplasma gondii Hypoxanthine-Guanine Phosphoribosyltransferase-GMP and -IMP Complexes: Comparison of Purine Binding Interactions with the XMP Complex. Biochemistry 38: 14485-14494, 1999.
E.L. White, L.M. Rose, P.W. Allan, R.W. Buckheit, Jr., W.M. Shannon, and J.A. Secrist III. Polyamine Pools in Human Immunodeficiency Virus Infected Cells. JAIDS 17:101-103, 1998.
E.L. White, B.J. Bowdon, and W.M. Shannon. Safety Factors Involved in the Extraction of Biologically Active Proteins from Human Immunodeficiency Virus. J. Virol. Methods 70:113-115, 1998.
E. L. White, L.J. Ross, S.M. Schmid, G.J. Kelloff, V.E. Steele, and D.L. Hill. Screening of Potential Cancer Preventing Chemicals for Induction of Glutathione in Rat Liver Cells. Oncology Reports 5:507-512, 1998.
E.L. White, L.J. Ross, S.M. Schmid, G.J. Kelloff, V.E. Steele, and D.L. Hill. Screening of Potential Cancer-Preventing Chemicals for Inhibition of Induction of Ornithine Decarboxylase in Epithelial Cells from Rat Trachea. Oncology Reports 5:717-722, 1998.
E.L. White, L. Westbrook, M.G. Hollingshead, and W.M. Shannon. Optimization of the Reverse Transcriptase Assay for the Detection of Viral Burden in Mice Infected with Rauscher Murine Leukemia Virus. J. Virol. 62:63-70, 1996.
R.W. Buckheit, Jr., E.L. White, J. Germany-Decker, L.B. Allen, L.J. Ross, W.M. Shannon, P.A.J. Janssen, and M.A. Chirigos. Cell-based and Biochemical Analysis of the Anti-HIV Activity of Combinations of 3'-Azido-3'-deoxythymidine and Analogues of TIBO. Antiviral Chem. & Chemother. 5:35-42,1994.
E.L. White, G. Arnett, J.A. Secrist III, and W.M. Shannon. Characterization of S-Adenosylmethionine Decarboxylase Induced by Human Cytomegalovirus Infection. Virus Res. 31:255-263, 1994.
E.L. White, W.B. Parker, L.J. Ross, and W.M. Shannon. Lack of Synergy in the Inhibition of HIV-1 Reverse Transcriptase by Combinations of the 5'-Triphosphates of Various Anti-HIV Nucleoside Analogs. Antiviral Res.22:295-308, 1993.
E.L. White, R.W. Buckheit, Jr., L.J. Ross, J.M. Germany, K. Andries, R. Pauwels, P.A.J. Janssen, W.M. Shannon, and Michael A. Chirigos. A TIBO Derivative, R82913, is a Potent Inhibitor of HIV-1 Reverse Transcriptase with Heteropolymer Templates. Antiviral Res. 16:257-267, 1991.
W.B. Parker, E.L. White, S.C. Shaddix, L.J. Ross, R.W. Buckheit, Jr., J.M. Germany, J.A. Secrist III, R. Vince, and W.M. Shannon. Mechanism of Inhibition of Human Immunodeficiency Virus Type 1 Reverse Transcriptase and Human DNA Polymerases α, β, γ and by the 5'-Triphosphates of Carbovir, 3'-Azido-3'-Deoxythymidine, 2',3'-Dideoxyguanosine, and 3'-Deoxythymidine. A Novel RNA Template for the Evaluation of Antiretroviral Drugs. J. Biol. Chem. 266:1754-1762, 1991.
E.L. White. A Novel RNA Template for the Study of Reverse Transcriptase Inhibitors and Its Application for Understanding the Nature of the TIBO Binding Site. Wiss. Zeitschrift der Humboldt-Universität zu Berlin R. Medizin 40:44-47, 1991.
D.L. Noah, E.L. White, and J.W. Noah. Development of High-Throughput Assays for Influenza, in Combating the Threat of Avian Influenza: Drug Discovery Approaches, Paul F. Torrence (ed), Willey and Sons (pub), Chapter2; p38-72 (2007).
C.B. Jonsson, E.L. White, W. Severson, and J. Noah. Going Hot - Creating a Roadmap for High Throughput Screening for Drug Discovery in Biosafety Level 3 Laboratories. Amer. Biotech. Lab. Accepted 2007.
C.B. Jonsson and E.L. White. Launching an HTS Campaign to Discover New Antivirals. Eur. Pharma. Rev. 3:36-39, 2007.
C.B. Jonsson, E.L. White, J. Noah, W. Severson, and M. Heil. The Search for Promising Viral Targets in Drug Discovery. Amer. Biotech. Lab. Vol. 25, August 2007.