Westbrook, L.W., Ramanathan, H. N., Isayeva, T., Roy-Mittal, A., Qu, Z., Johnson, M.D., Kern, F. G., Ponnazhagan, S., Grubbs, C.J., Thottassery, J.V. High Cks1 expression in transgenic and carcinogen-initiated mammary tumors is not accompanied by p27Kip1 loss Int. J. Oncology 34:1425-1432, 2009.
Secrist, J. A, Thottassery, J.V. and Parker, W. B. Clofarabine: From Design to Approval. In Herdeweijn,P. (Ed) Modified Nucleosides: in Biochemistry, Biotechnology and Medicine (pp 629-644). Wiley 2008.
Zhican Qu, Van Ginkel, S., Roy-Mittal, A., Nasrin, M., Westbrook, L.W., Carey, D., Li, R., Grizzle, W.E., Thottassery, J.V., Kern, F.G., VEGFA165 Reduces Tamoxifen Efficacy and Promotes Metastatic Colonization, and Desmoplasia in Breast Tumors. Cancer Research 68 (15):,6232-6240, 2008.
Westbrook, L. W., Manuvakhova, M., Kern, F., Estes II, N.R., Ramanathan, H. and Thottassery, J.V. Cks1 Regulates Expression of Cdk1: A Novel Role During Mitotic Entry in Breast Cancer Cells. Cancer Research 67:11393-401, 2007.
Zhican Qu, Van Ginkel, S., Roy-Mittal, A., Nasrin, M., Thottassery, J.V., Westbrook, L.W., Carey, D., Li, R., Grizzle, W.E., Kern, F.G., VEGFA Reduces Tamoxifen Efficacy and Promotes Metastatic Colonization, and Desmoplasia in Breast Tumors Cancer Research 68:6232-40, 2008.
Estes, N. R. II, Thottassery, J. V., Louise Westbrook, Kern, F. G. MEK Ablation in MCF-7 Cells Blocks DNA Synthesis Induced by Serum, but not by Estradiol or Growth Factors. Int. J. Oncology 29:1573-1580, 2006.
Estes, N. R. II, Thottassery, J. V., and Kern F.G. siRNA mediated knockdown of fibroblast growth factor receptors 1 or 3 inhibits FGF-induced anchorage-independent clonogenicity but does not affect MAPK activation. Oncology Reports 15: 1407-1416, 2006.
Thottassery, J.V., Westbrook, L.W., Someya, H., and Parker W.B. c-Abl independent p73 stabilization during Gemcitabine or 4'-Thio-β-D-arabinofuranosyl cytosine (T-araC) induced apoptosis in wild-type and p53-null colorectal cancer cells. Molecular Cancer Therapeutics 5: 400-410, 2006.
Manuvakhova, M., Thottassery, J.V., Susan Hays, Kern, F.G. Expression of SNT-1 Phosphotyrosine Binding Domain inhibits Activation of MAP kinase and PI-3-kinase pathways and Antiestrogen-resistant Growth Induced by FGF-1 in Breast Cancer Cells. Oncogene 25: 6003-6014, 2006.
Sadlonova, A., Johnson, M. R., Bowe, D. B., Moore, C. S., Gault, S.R., Page, G. P., Thottassery, J. V., Welch D.R. and Frost, A.R. Primary Breast Fibroblasts Modulate Epithelial Cell Proliferation in Three-Dimensional In Vitro Co-Culture. Breast Cancer Res 7: R46-R49, 2005.
Thottassery, J.V., Yanjie Sun, Louise Westbrook, Sarah Rentz, Marina Manuvakhova, Zhican Qu, Shanti Samuel, Ramanda Upshaw, Amanda Poe, and Kern, F.G. Prolonged MEK-ERK 1/2 Activation During FGF-1 or Heregulin β1 Induced Antiestrogen-Resistant Growth of Breast Cancer Cells is Resistant to MEK Blockers. Cancer Research 64: 4637-4647, 2004.
Thottassery, J.V., Zhican Qu, Van Ginkel, S., Manuvakhova, M., Westbrook, L., Roland-Lazenby, C., Hays, S, and Kern F.G. Homogeneity and Long-Term Stability of Tetracycline-Regulated Gene Expression with Low Basal Activity by using the rtTA2S-M2 Transactivator and Insulator-flanked Reporter Vectors. Gene 327:61-73, 2004.
Thummel K. E., Brimer, C. Yasuda, K., Thottassery, J., Senn, T., Lin, Y., Ishizuka, H., Kharasch, E., Schuetz, J., and Schuetz, E. Transcriptional Control of Intestinal CYP3A4 by 1α ,25-Dihydroxy Vitamin D3. Molecular Pharmacology 60:1399-1406, 2001.
Lecureur, V., Thottassery, J. V., Zambetti, G. P., Sun, D., Schuetz, E.G. and Schuetz, J. D. Mdr1b Facilitates p53-Mediated Cell Death and p53 is required for Mdr1b Upregulation in vivo. Oncogene 20:303-313, 2001.
Thottassery J. V., Zambetti, G.P., Daxi Sun, Troutman, A., Sukhatme, V.P., Schuetz, E.G., and Schuetz, J.D. Sp1 and Egr-1 Have Opposing Effects on the Regulation of the Rat Pgp2/mdr1b Gene. J. Biol Chem 274: 3199-3206, 1999.
Thottassery, J.V., Zambetti, G. P., Arimori, K., Schuetz, E.G. and Schuetz, J. D. p53-Dependent regulation of MDR1 gene expression causes selective resistance to chemotherapeutic agents. Proc. Natl. Acad. Sci. USA 94:11037-11042, 1997.
Furuya, K., Thottassery, J. V., Schuetz, E. and Schuetz, J. Bromocriptine transcriptionally activates the multidrug resistance (pgp2/mdr1b) gene by a Novel Pathway. J. Biol. Chem. 272:11518-11525, 1997.
Schuetz J. D., Schuetz E. G., Thottassery J. V., Guzelian P.S., Strom, S., and Sun, D. Identification of a Novel Dexamethasone Responsive Enhancer in the Human CYP3A5 Gene and its Activation in Human and Rat Liver Cells. Molecular Pharmacology 49: 63-72, 1996.
Schuetz, J. D., Silverman J. A., Thottassery J. V., Furuya, K. N., and Schuetz, E. G., Divergent Regulation of the Class II P-glycoprotein Gene in Primary Cultures of Hepatocytes versus H35 Hepatoma by Glucocorticoids, Cell Growth and Differentiation 6:1321-1332, 1995.
Nyquist-Battie C., Hagler K.E., Winberg L. and Thottassery J.V., Acetylcholine Levels, Choline Acetyltransferase and Acetylcholinesterase Molecular Forms During Thyroxine-induced Cardiac Hypertrophy. Neurochem. Int. 22(2):143-151, 1993.
Yarbrough J.D., Grimley J. and Thottassery J.V., Mirex-Induced Adaptive Liver Growth in Rats Subjected to Thyroidectomy. Hepatology 15:923-927, 1992.
Thottassery J., Winberg, L., Cunningham, M. and Badr, M., Regulation of Perfluorooctanoic Acid-Induced Peroxisomal Enzyme Activities and Hepatocellular Growth by Adrenal Hormones. Hepatology 15:316-322, 1992.
Thottassery J.V. and Yarbrough J.D., Regulation of Glucocorticoid Receptors During Adaptive Liver Growth. Am. J. Physiol. 260: G603-G609, 1991.